1164 Lipid Metabolism Profile 2.0 (Blood)
In recent year, people with hyperlipidemia increase year after year in Taiwan, and their age becomes younger. Common causes of hyperlipidemia are genetic inheritance, diseases (like diabetes, obesity, Cushing’s disease, nephrotic syndrome, hypothyroidism), dietary habit and binge drinking. Researches suggest, beside cardiovascular diseases, hyperlipidemia causes cerebral vascular disease(a.k.a. stroke), hypertension, diabetes and other chronic diseases. Because of this, we should take seriously the prevention and treatment of hyperlipidemia. Lipid Metabolism Profile 2.0 not only detects blood triglyceride, cholesterol and their balancing ratio, but also includes lipoprotein meta-analysis, which gives us more information for evaluating risk of coronary atherosclerosis.
Testing Content
Cardiovascular disease
Cardiovascular disease is closely related to both genetic predisposition and environmental and lifestyle factors, including diet and physical activity. Traditional blood lipid markers, such as cholesterol and triglyceride abnormalities, account for only about 50% of cardiovascular disease cases. In light of this, improving clinical diagnostic tools is essential for accurately identifying cardiovascular risk.
Beyond conventional lipid testing, lipid metabolism health assessments include analysis of HDL subtypes, non-HDL cholesterol (non-HDL-C), and lipoprotein(a). These assessments combine traditional and advanced analytical technologies, offering valuable insights for you and your clients’ personalized health management plans. This enables the timely implementation of preventive treatments to reduce or eliminate multiple cardiovascular risk factors.
non-HDL-C
non-HDL-C refers to the total amount of cholesterol carried by very-low-density lipoprotein (VLDL-C), low-density lipoprotein (LDL-C), intermediate-density lipoprotein (IDL-C), and lipoprotein(a) cholesterol. It is calculated by subtracting HDL cholesterol from total cholesterol. These lipoproteins are considered to be associated with arterial wall thickening (atherosclerosis) and contribute to the formation of foam cells and the acceleration of fatty plaque buildup. The U.S. National Cholesterol Education Program suggests that measuring non-HDL-C may serve as a better predictor of cardiovascular disease risk.
| Lipid Metabolism Profile can be analyzed | |
|---|---|
| Dyslipidemia | Metabolic syndrome |
| Obesity | Artery disease |
| Heart disease | |
The important information provided by Lipid Metabolism Profile is as follows
- Triglycerides
In addition to being associated with cardiovascular disease, chronically high triglyceride levels can lead to insulin resistance, resulting in poor glucose utilization and eventually causing diabetes. - Lipoprotein (a)
It is genetically determined and is minimally affected by environmental factors. Individuals with high levels of lipoprotein(a) have a higher risk of developing cardiovascular disease compared to those with normal levels. - Apolipoproteins
An increase in apolipoprotein B (apoB) levels raises the risk of developing coronary atherosclerosis, while apolipoprotein A1 (apoA1) serves as a protective marker against vascular hardening. Clinically, the ratio of apoB to apoA1 is often used to assess the risk of coronary artery disease. - Balanced Ratio
According to epidemiological studies, the apoB/apoA1 ratio can be used to estimate the risk (hazard ratio) of cardiovascular disease. It is not only one of the best indicators in epidemiological research but also an optimal marker for guiding treatment.
