Menopause

Menopause refers to the transitional period during which a woman's ovarian function gradually declines from normal to non-functional. During this phase, the decrease in estrogen secretion from the ovaries may lead to various physical discomforts, such as hot flashes, palpitations, mood instability, and skin atrophy, collectively known as "menopausal disorders." The most noticeable phenomenon for women is the cessation of menstruation, which is why "menopausal disorders" are also referred to as "menopause syndrome." In fact, these disorders can begin as early as the decline in ovarian function around the age of 35, not necessarily after menopause, which typically occurs around the age of 50.

Estrogen Dominance

Estrogen and progesterone levels gradually decrease with age, especially during the perimenopausal to postmenopausal period, where a rapid decline occurs. Between ages 35 and 50, progesterone production decreases by approximately 75%, while estrogen declines by about 35%. After menopause, progesterone levels can drop up to 50 times, whereas estrogen remains at about 50% of its premenopausal levels. As estrogen levels gradually decrease and progesterone becomes significantly insufficient, progesterone can no longer counterbalance estrogen in the body. This condition is known as "Estrogen Dominance. "

Premenopausal Hormone-META^® assessable

• Prevent and treat postmenopausal syndromes and symptoms.
• Maintain physiological balance between androgen and estrogen metabolism.
• Serve as a basis for formulating Hormone Replacement Therapy (HRT) or monitoring treatment outcomes.

Premenopausal Hormone-META® can prevent or treat the following related diseases and symptoms
Cognition and Emotion	Ovarian Dysfunction	Other Related Diseases and Symptoms
Anxiety & Depression	Menopausal symptoms	Muscle Weakness and Atrophy
Fatigue	(e.g., hot flashes, palpitations, mood instability, skin atrophy)	Hypoglycemia and Diabetes
Poor memory	Osteoporosis	Mellitus (CVD)
Loss of libido		Headache / Migraine
		Sexual Dysfunction

The important information provided byostmenopausal Hormone-META^® is as follows

• Assess the integrity of the Hypothalamus/Pituitary/Adrenal/Ovary (HPAO) axis's endocrine physiological balance.
• Understand the relationship between hormones and diseases such as breast cancer, osteoporosis, dementia, and cardiovascular diseases.
• Understand hormonal changes before and after menopause.
• Examine the balance between stress and anti-stress hormones: This can reflect the changes in adrenal cortex hormones during different stress periods and their physiological coordination.
• ress balance index (Cortisol/DHEA): This can serve as an indicator of health status and aging. These two hormones have an inverse relationship; imbalance can reduce the body's ability to withstand stress.
• Understand the physiological balance between gonadal steroid hormones, which can assist physicians in formulating personalized health management plans.
• Aid in selecting personalized bioidentical hormone replacement therapy (BHRT) and monitoring its effectiveness and safety.