1295 TruAge COMPLETE
TruAge COMPLETE is exclusively licensed by the U.S.-based True Diagnostic™ Laboratory to Hans Functional Medicine Laboratory, with joint technology development integrating scientific research teams from Harvard University, Yale University, and Duke University. It utilizes a non–closed (fully traceable) algorithmic framework, analyzing over 950,000 CpG genomic sites and measuring more than 75 key biomarkers that influence healthspan development. This assessment provides the most extensive, precise, and clinically accurate biological age and actionable health information currently available worldwide. The evaluation delivers comprehensive insights ranging from aging pace tracking and organ health–related longevity biomarkers to precision assessments of cancer risk and alcohol-related risk, enabling highly accurate and practical health predictions.
Testing Content
OMICm Age
The TrueAge test is an epigenetic analysis that examines how changes in your DNA actually affect your health. This innovative epigenetic test uses markers on DNA known as methylation to predict your biological age.
Biological age is a predictor of healthspan and can be linked to the risk of various age-related diseases, such as Alzheimer’s disease and cancer. Ideally, having a biological age that is younger than your chronological age indicates a healthy lifestyle that may help protect you from disease.
SYNPHONEYAge
SYMPHONYAge provides a groundbreaking approach to aging assessment by independently and simultaneously evaluating multiple organ systems. This unique epigenetic aging algorithm assesses specific organs such as the brain, liver, heart, and immune system, allowing us to understand how different parts of the body age individually.
With the results from SYMPHONYAge, you can make more informed lifestyle choices and targeted medical decisions to optimize your overall health and slow the aging process.
DunedinPACE
It allows an individual’s rate of aging and biological age to be quantified—like a dynamic aging speedometer—rather than merely determining age at a single fixed point in time. By combining biological age measurement (OMICmAge) with real-time aging pace assessment (DunedinPACE), it becomes possible to gain deeper insights into the aging process, predict disease risk, and enable more effective preventive health management.
Telomere
Telomeres are repetitive DNA sequences located at the ends of chromosomes. They function like protective caps, preventing chromosomes from being damaged during cell division. Under normal physiological conditions, telomere length shortens with each cell division. Eventually, telomeres lose their protective function, and cells undergo apoptosis when they can no longer divide.
When telomeres are relatively short, it indicates that the body has been in a state of chronic inflammation and oxidative stress for an extended period, and it is associated with a higher risk of chronic diseases, such as cardiovascular, pulmonary, and immune system degenerative disorders.
| Potential Symptoms and Disease Risks of Biological Aging | |
|---|---|
| Cardiovascular disease | Insulin resistance |
| Diabetes mellitus | Aging |
| Asthma | Pulmonary fibrosis |
| Cognitive decline | Alzheimer's disease |
| Depression | Osteoporosis |
The important information provided by TruAge COMPLETE is as follows
- Assessing Organ-Specific Aging and Disease Risk
The SYMPHONYAge report provides independent evaluations of the aging processes of individual organ systems. The body’s systems do not age in isolation; many age-related diseases arise from imbalances in the coordinated functioning of multiple physiological systems. These interconnected imbalances lead to different aging patterns, making some individuals more susceptible to certain system-specific age-related diseases. This highlights the need for personalized care strategies focused on improving the function of specific organs. - Evaluating Annual Aging Pace and Potential Risks
DunedinPACE reveals how many biological years you age per chronological year. An accelerated aging pace reflects the cumulative effects of lifelong stress on DNA methylation and is associated with a higher risk of chronic diseases and mortality. - Measuring Telomere Length and Relative Aging Risk
Biological aging status is assessed by comparing telomere length with that of age-matched peers. Telomeres naturally shorten with age, and chronic inflammation and oxidative stress can accelerate this shortening, leading to premature aging. - Examining the Impact of Lifestyle on Biological Aging
Through DNA methylation–related modules, the analysis evaluates how smoking and alcohol consumption affect biological age and accelerated aging.